Product OverviewCryoDerm is a soothing Cold Therapy topical analgesic gel for pain relief. Cryoderm gel penetrates the muscle while giving an instant cooling sensation for targeted cryotherapy. For this reason, Cryoderm Cold Therapy Pain Relief is used in sports medicine, chiropractic, physical rehabilitation, and massage, but it’s also an ideal solution for active individuals who put their bodies to the test. It comes in a variety of sizes and applicator options, such as spray, gel, roll-on gel, and CryoDerm 1-gallon bottles.Cryoderm UsesMuscle StrainsSore MusclesJoint PainBackacheArthritisSwelling in the JointsSprained LigamentsKnee PainBruisesTraditional Massage, Myofascial Release, and Trigger Point MassageHow It Works The CryoDerm offers clinical-strength pain relief that effectively reduces pain and muscle spasms. The all-natural formula incorporates essential oils and extracts with a concentration of menthol to create a long-lasting cooling effect to treat pain and increase blood flow to remove inflammation.The Power of Menthol USPMenthol USP is an organic compound that’s extracted from the peppermint plant. The compound produces a cooling sensation that significantly reduces pain intensity. The cooling effect is soothing, but it’s also triggering the skin’s cold receptor neurons to mitigate pain reception. Its natural cooling properties have been clinically proven to offer pain relief and reduce inflammation.1 Often the pain is related to swelling and menthol also has an anti-inflammatory role. Together with the active ingredients Arnica and Boswellia, blood flow is increased to reduce inflammation to further reduce pain and discomfort. CryoDerm Pain Relief products have a higher menthol concentration — 10% — than similar products like Biofreeze, which uses 5% menthol. Other Active Ingredients Peppermint Oil: Peppermint delivers a burning-cold sensation. It also has anesthetic properties and promotes blood flow.Arnica: This yellow herb is diluted to reduce pain and reduce inflammation to be helpful with muscle soreness, joint irritation, and swelling.Eucalyptus: Its leaves contain antioxidants that fight bacteria and have pain-relieving properties.Ilex: Is a leaf from the Holly tree and is used to loosen the joint and reduce swelling.How to ApplyThere are many applicator options. The gel can be dispensed from a pump bottle, packet, spray, and roll-on and massaged into the skin. CryoDerm Roll-On applicator easily glides against the skin to spread the gel on the affected area. The CryoDerm spray evenly distributes the formula and can be left alone to dry or it can be massaged into the skin.Repeat as necessary, up to four times a day.Features and BenefitsOffers Fast, Penetrating Pain ReliefApplies Colorless With No MessReduces InflammationGreaseless, Non-StainingHigher Content of Soothing MentholUses Natural Menthol, Essential Oils and ExtractsPowerful CryotherapyCryoDerm 1-Gallon Bottle Ideal for ClinicsProduct SpecificationsManufacturer: CryoDermProduct Numbers: CRO100, CRO101, CRO102, CRO103, CRO104, CRO105, CRO106, CRO109, CRO110Made in the U.S.Variations: Packet, Spray, Roll-On, Gel, or Pump BottleHCPCS: A9270Menthol Strength: 10%IngredientsMenthol USP, Arnica Montana Flower, Boswellia, Eucalyptus Oil, Glycerin, Ilex Paraguariensis Leaf, Dimethyl Sulfone, Peppermint Oil, Purified Water, Alcohol, Trolamine, Alklyl Methacrylate EsterWarningConsult with a health care professional before use if pregnant or breastfeeding.Keep away from excessive heat or an open flame.If redness or irritation is present after use, stop, and wash off.External use only.Complementary Products Pro-Lite 3D Knee Support Thermoderm Heat Lotion Soft Comfort CorPak Hot/Cold PacksManuals and Documents    Brochure    Label Information   Footnotes1 Heggers, John P., et al. “Acute Effect of Topical Menthol on Chronic Pain in Slaughterhouse Workers with Carpal Tunnel Syndrome: Triple-Blind, Randomized Placebo-Controlled Trial.” US National Library of Medicine National Institutes of Health (Last Accessed September-15-2014)Product Videos   How CryDerm Works Video (2:56 minutes)